Integrin beta 3 anticorps

N° du produit ABIN6158012

Cet anticorps anti-Integrin beta 3 est un anticorps Souris Monoclonal détectant Integrin beta 3 dans FACS, IF et AGG. Adapté pour Humain.

Aperçu rapide pour Integrin beta 3 anticorps (ABIN6158012)

Antigène: Integrin beta 3 (ITGB3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 3 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Aggregation (AGG)

Clone: 2-50E 12

Détail du produit anti-Integrin beta 3 anticorps

Fonction: Mouse Monoclonal anti-CD61 (25E11), Purified, BSA-free

Attributs du produit: This antibody recognizes human integrin beta3 (GPIIIa, vitronectin receptor beta chain). The protein detectable is a complex of CD41 and CD61.The apparent molecular weight of the GPIIIa by SDS-PAGE is 105 kDa reduced and 90 kDa unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Purification: Purified

Immunogène: Normal blood mononuclear cells activated by mixed lymphocyte reaction

Isotype: IgM kappa

Information d'application

Indications d'application: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Inhibits platelet aggregation
• Optimal dilution for a specific application should be determined by user

Commentaires:

U937, KG1a, HEL cells, and human platelets in lymph nodes or tonsils.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS (no BSA, no azide)

Agent conservateur: Azide free

Détails sur Integrin beta 3

Antigène: Integrin beta 3 (ITGB3)

Autre désignation: CD61

Sujet: BDPLT2, GP3A, GPIIIa, GT, HPA 1, HPA 4, Integrin beta-3, ITGB3, NAIT, Platelet fibrinogen receptor beta subunit, Platelet glycoprotein IIIa, PTP

Poids moléculaire: 105 kDa & 90 kDa

ID gène: 3690, 218040

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex